TREATMENT OF STAT5B-RARA POSITIVE ACUTE PROMYELOCYTIC LEUKEMIA BY VENETOCLAX COMBINING WITH HOMOHARRINGTONINE, CYTARABINE: A CASE REPORT AND LITERATURE REVIEW

Abstract.Introduction:.Acute promyelocytic leukemia (APL) is mostly due to the chromosome translocation t (15; 17) (q22; q12), leading to the formation of PML-RARA fusion protein.Some patients carried rare translocation involving RARA gene, who Gyutoh were called variant APL caused by RAR family (RARA, RARB, and RARG) and partner genes.STAT5b-RARA

We consider the questions of one value solvability lattigo of the nonlocal boundary value problem for a nonlinear ordinary integro-differential equation with a degenerate kernel and a reflective argument.The method of the degenerate kernel is developed for the case of considering ordinary integro-differential equation of the first order.After denot

High-fat/high-carbohydrate diets have been proved to be associated with series metabolic syndromes and can lead to non-communicable diseases.In this paper, recent cohort studies and Vibrators animal experiments about the influences of macro-nutrients (carbohydrate, fat and protein) with different ratios to organisms were overviewed.The results base

The purpose of this study is threefold: first, to study factors that affect the decision making of hotel and lodging entrepreneurs in SALTED PUMPKIN SEEDS the area of Nonthaburi and Pathum Thani in Thailand when selecting investment patterns; second, to create a fit pattern to solve financial liquidity problem; and third, to determine the appropria

We introduce a deviation-tolerance software architecture, which is devised for a prototype of a cloud-based harvest operation optimisation system issuing harvest plans.The deviation-tolerance architecture adapts the fault tolerance notions originating in the area of systems engineering to the harvest domain and embeds them into the Vienna developed